Food protein-induced enterocolitis to hen's egg.

Food protein–induced enterocolitis syndrome (FPIES) is potentially severe, non–IgE-mediated food hypersensitivity characterized by profuse emesis and diarrhea that progresses to dehydration and shock in 15% to 20% of patients. The diagnosis is based on clinical criteria and/or an oral food challenge (OFC). The pathophysiology of FPIES is not well characterized; the gastrointestinal T-cell response to food protein is a plausible mechanism. FPIES is usually caused by cow’s milk or soy in formula-fed infants; solids, such as rice, oat, barley, chicken, turkey, fish, and peanut, can also cause FPIES.We report the case of an infant with FPIES caused by hen’s egg and discuss the clinical features and differential diagnosis of FPIES.